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Sonderforschungsbereich 415:
"Specifity and Pathophysiology of Signal Transduction Pathways"
at Christian-Albrechts-University in Kiel
Project Groups
The National Research Center 415 is divided into four groups of projects:
| A2 | Sabine Adam | Institut für Immunologie |
| | Growth stimulatory and proapoptotic signals mediated by the death receptor-initiated FADD/Caspase-signaling pathway in murine fibroblasts |
| A3 | Holger Kalthoff | Molekulare Onkologie |
| | Analysis of molecular apoptosis resistance mechanisms of epithelial tumor cells |
| A4 | Dieter Adam | Institut für Immunologie |
| | Regulation of caspase-independent cell death and cell proliferation by sphingolipid mediators |
| A9 | Ottmar Janßen | Institut für Immunologie |
| | Regulation of Expression and Signal Transduction of the CD95 Ligand on T-Lymphocytes and Tumor Cells |
| A10 | S. Bulfone-Paus | FZ Borstel, Abt. Immunologie und Zellbiologie |
| | Molecular mechanisms of apoptosis-inhibition by interleukin-15 |
| A11 | Stefan Schütze | Institut für Immunologie |
| | Identification and functional characterization of intracellular ceramide-binding proteins |
| A12 | Thomas Herdegen | Institut für Pharmakologie |
| | c-Jun N-terminal kinases as effectors of neural degeneration in the adult brain |
| A13 | Heiner Schäfer | Labor für Molekulare Gastroenterologie |
| | Involvement of the early response gene p22PRG1/IEX-1 in the regulation of cell growth and cell viability |
| A14 | Dieter Kabelitz | Institut für Immunologie |
| | Role of TDAG51 in cellular activation, proliferation, and apoptosis |
| B2 | Ehrhardt Proksch | Klinik für Dermatologie |
| | TNF, IL-1 and IL-6 signal transduction pathways in wound healing |
| B5 | Stefan Rose-John | Institut für Biochemie |
| | The soluble interleukin-6 receptor: generation and physiologic function |
| B6 | Frank Petersen | FZ Borstel, Abt. Immunologie und Zellbiologie |
| | Activation of leukocytes by the CXC-chemokine platelet factor 4: Independent and cooperative signals |
| B7 | Joachim Grötzinger | Institut für Biochemie |
| | Solution structure of interleukin-6-receptor and gp130-extracellular domains by NMR-spectroscopy |
| C6 | Stefan Rose-John, Karl-Joseph Kallner | Institut für Biochemie |
| | Viral Interleukin-6: Strukture, Pathophysiology and Strategies of Neutralisation |
| C7 | Stefan Ehlers | FZ Borstel, Laborgruppe Molekulare Infektiologie |
| | The role of MAP kinases in receptor-mediated macrophage activation during mycobacterial infections |
| C8 | Stefan Schreiber | I. Medizinische Klinik |
| | Functional studies of TNF receptor p75 (CD 120b) |
| C9 | Jens-Michael Schröder | Klinik für Dermatologie, Venerologie und Allergologie |
| | The significance of Lipid-like leukocyte activators (LILA) and their receptors in inflammation |
| Z1 | Stefan Schreiber | I. Medizinische Klinik |
| | Systematic expression analysis |
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